GC-MS/MS CHROMTECH Evolution

Your Agilent MSD can do GC-MS/MS with CHROMTECH EVOLUTION

Do you already have an existing 5973, 5975 or 5977 in your lab? Are you considering buying a MS/MS? Why not upgrade your existing unit?

Any analysis with difficult matrices will benefit from the MS/MS upgrade. Consider analyses for anti-doping, forensics, and drug testing; of pesticide and herbicide residues in food or marijuana, biomarkers in oil exploration, dioxin traces, and PCBs in feed and food. If sample cleanup is hampering your limit of detection, the second quad will do the work for you.

What does a GC/MS/MS do?

When a second phase of mass fragmentation is added, a second quadrupole behind an existing Agilent quadrupole MSD, it is called tandem MS (MS/MS). MS/MS is better suited to quantifying low levels of target compounds such as pesticides, drugs of abuse, and biomarkers in the presence of a high sample matrix background.

To be more precise, the first quadrupole (Quad 1), in our case the existing Agilent MSD quad, is connected by means of a 90-degree collision cell (Quad 2) and another quadrupole (Quad 3) made by CHROMTECH GmbH. Both quadrupoles can be used in scanning or static mode, depending on the type of MS/MS analysis being performed. Types of analysis include product ion scans, precursor ion scans, multiple reaction monitoring or MRM and neutral loss scans.

Here is a typical procedure to develop a method for one compound of interest:

When Quad 1 is in static mode (looking at one mass only as in SIM), and Quad 3 is in scanning mode, you obtain a so-called product ion spectrum (also called "daughter spectrum"). From this spectrum, you can select a prominent product ion (possibly one which is not dominant in the matrix), which is the product ion for the precursor ion you choose. The pair is called a "transition" and forms the basis for MRM. MRM is highly specific and virtually eliminates matrix background entirely.

Are you compliant with the EPAs feed, food, food crops or marijuana import and export regulations?

Are you looking for one of the following 820 pesticides or herbicides? If so, the Evolution GC/MS/MS has you covered. You don’t need to develop a method, just prepare your sample and get your result.

Acenaphthene Chloro-2-nitrotoluene, 4- Ethion MCPD, 3- Phenkapton, Acenaphthylene Chloro-3-methylphenol, 4- Ethofenprox Mecarbam Phenothrin, Acephate Chloro-3-nitrobenzene, 1- Ethoprophos Mepanipyrim Phenylphenol, oAcetamiprid, Chloro-3-nitrobenzene, 2- Ethoxazole Meptyldinocap Phorate, Aclonifen Chloro-3-nitrobenzene, 4- Ethoxyquin Metalaxyl Phosalone, Acrinatrina Chloro-4-nitrobenzene, 1- Ethylcarbamat Metalaxyl-M Phosmet, Alachlor Chloro-4-toluidine, 2- Ethylcarbamat, d5- Methabenzthiazuron Phosphamidon, Aldrin Chloro-6-nitrotoluene, 2- Etridiazole Methacrifos Phthalimide, Ametryn Chlorothalonil Etrimfos Methamidophos Piperonyl butoxide, Amitraz Chlorphenol, 2- Famoxadone Methidathion Pirimicarb, Anilofos Chlorphenol, 3- Fenamiphos Methoxychlor Pirimiphos-ethyl, Anthracene Chlorphenol, 4- Fenarimol Methylparaben Pirimiphos-methyl, Anthracene, d10- Chlorpropham Fenazaquin Metolachlor Prallethrin, Anti Ox Chlorpropylat Fenbuconazole Metribuzin Prochloraz, Aramit Chlorpyriphos-ethyl Fenchlorphos Mevinphos Procymidone, Atrazin Chlorpyriphos-methyl Fenhexamid Mirex Profenofos, Azaconazole Chlorthal-dimethyl Fenitrothion Molinate Profluralin, Azinphos-ethyl Chlorthion Fenobucarb Monocrotophos Prometryn, Azinphos-methyl Chlozolinate Fenoxaprop-p-ethyl Monolinuron Propachlor, Azoxystrobin Chrysene Fenpropathrin Monophenyltin Propamocarb, Benalaxyl Cinerin I Fenson Myclobutanil Propanil, Benfluralin Cinerin II Fenthion Naphthalene Propargite, Benoxacor Tetrahydrophthalimid Fenvalerate Nitrapyrin Propazine, Bentazone Clodinafop-propargyl Fipronil Nitrofen Propham, Benzidine Coumaphos Fipronil Nitrothal-isopropyl Propiconazole-II /-I, Benzo[a]anthracene Cumene Flamprop-methyl Nonadienal, 2,4- Propoxur, Benzo[a]pyrene Cyanophos Flonicamid Nonylphenol Propylparaben, Benzo[b]fluoranthene Cyfluthrine I-IV Flubenzimin Nuarimol Propyzamide, Benzo[g,h,i]perylene Cyhalothrin, lambda- Flucythrinat Octanal Proquinazid, Benzo[k]fluoranthene Cymoxanil Fludioxonil Octenal, 2- Prothiophos, Benzofuran, 2-Methyl- Cypermethrin I / II / II / IV Flufenacet Omethoate Pyraclofos, Benzophenone Cypermethrin, -alpha Fluoranthene Ovex Pyrazophos, Benzophenone, 4-methyl- Cyproconazole -1/-2 Fluorene Oxadiazon Pyrethrin I, Benzophenone, 4-phenyl Cyprodinil Fluotrimazol Oxadixyl Pyrethrin II, Benzylbenzoate, methyl-2- DDD, o,p- Fluquinconazol Oxyfluorfen Pyridaben, Bifenox DDD, p,p- Fluroxypyr-methyl Paclobutrazol Pyrimethanil, Bifenthrin DDE, o,p- Flusilazole Paraoxon Quinalphos, Binapacryl DDE, p,p- Fluvalinate, tau- Paraoxon-methyl Quinoxifen, Bioresmethrin DDT, o,p- Folpet Parathion-ethyl Quintozen, Biphenyl DDT, p,p- Fonofos Parathion-methyl Resmethrin Bitertanol Deltamethrin Formothion PBDE 100 Silafluofen, Boscalid Demeton-methyl Fuberidazole PBDE 100 Simazin Bromacil Demeton-O Furalaxyl PBDE 153 Spirodiclofen, Bromobutide Demeton-S-methyl Halfenprox PBDE 153 Spiroxamine 1 / 2, Bromocyclen Desmetryn HCB PBDE 154 Sulfur (S8), Bromophos-ethyl Diallate HCH, alpha- PBDE 154 TCMTB, Bromophos-methyl Diazinon HCH, beta- PBDE 190 Tebuconazole, Bromopropylat Dibenzo[a,h]anthracene HCH, delta- PBDE 28 Tebufenpyrad, Bromuconazol Dibenzofuran HCH, e PBDE 28 Tecnacene, Bupirimate Dibutyltin (Ethylderivative) HCH, gamma- (Lindane) PBDE 47 Tefluthrin, Buprofezin Dichlobenil Heptachlor PBDE 47 Telodrin, Butachlor Dichlofluanid Heptachlorepoxid, (endo, A) PBDE 99 Terbacil, Butadiene, Hexachloro-1,3- Dichloroaniline, 3,4- Heptachlorepoxid, (exo, A) PBDE 99 Terbufos, Butamifos Dichlorvos Heptachlorepoxid, trans PCB 101 Terbutryn, Butralin Diclobutrazole Heptadienal, 2,4- PCB 105 Terbutylazin, Butylparaben Dicloran Heptenophos PCB 138 Tetrachlorvinphos, Cadusafos Dicofol Hexaconazole PCB 153 Tetraconazole, Cafenstrole Dicrotophos Hexazinone PCB 156 Tetradifon, Captafol Dieldrin Hexyl Cinnamic aldehyde PCB 157 Tetramethrin, Captan Difenoconazole HMS PCB 169 Thiabendazole, Carbaryl Diflufenican Imazalil PCB 18 Thiobencarb, Carbofuran Diisobutylphthalate Indeno[1,2,3-c,d]pyrene PCB 180 Thiometon, Carbophenothion Dimethoat Indoxacarb PCB 194 TnBP, Chinomethionat Dimethomorph-E Iprobenphos PCB 196 Tolclofos-methyl, Chloraniline, 2- Dimethomorph-Z Iprodione PCB 28 Tolylfluanid, Chloraniline, 3- Diphenylamine Iprovalicarb PCB 29 Triadimefon, Chloraniline, 4- Ditalimfos Isocarbophos PCB 31 Triadimenol, Chlorantraniliprole Diuron Isofenphos PCB 52 Triazophos, Chlorbensid DMST Isofenphos-methyl PCP Tribromanisol, 2,4,6-Chlorbenzilate Endosulfan sulfate Isopropalin Penconazole Trichloranisol, 2,4,6-Chlorbufam Endosulfan, a- Isopropylthioxanthon, 2- Pendimetalin Trichlorobenzene, 1,2,4-Chlordan, cis- /trans- Endosulfan, a- / b- Isopropylthioxanthon, 4- Pendimethanil Trichloronate, Chlordecon Endosulfan, b- Jasmoline I Pentachloroanilin Trifloxistrobin, Chlordene, 1-Hydroxy- Endrine Jasmoline II Pentachloroanisole Trifluralin, Chlorfenapyr EPN Kresoxim-methyl Pentachlorobenzole Triphenyltin (Ethylderivative), Chlorfenson Epoxiconazole Linuron Permethrin-I / -II Vernolate, Chlorfenvinphos Esfenvalerate Malaoxon Perthan Vinclozolin, Chloro-2,4-dinitrobenzene, 1- Ethafluralin Malathion Phenanthrene Zoxamide

Presentation of the CHROMTECH EVOLUTION triple quadrupole GC-MS/MS system

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Chromtech Evolution Tech Specs

Chromtech Evolution Brochure

We can upgrade any Agilent 5977, 5975 or 5973 MSD to a GC-MS/MS, GC QQQ or tandem MS system called EVOLUTION.

Your Agilent MSD can do GC-MS/MS with CHROMTECH EVOLUTION